A new assay system for studying human receptors involved in cell signaling.
Highly Multiplexed Cell-Based GPCR Assay.
['FUNDING_SBIR_2'] · SPECTRAGENETICS · NIH-10794227
This study is working on a new way to quickly test how certain proteins in your body respond to different substances, which could help create better and safer medicines for people like you.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SPECTRAGENETICS (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-10794227 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a novel assay system that can detect and measure how human receptors, specifically G protein-coupled receptors (GPCRs), respond to various substances. By using a miniaturized and scalable approach, the project aims to screen large numbers of these receptors simultaneously, which could significantly enhance the drug discovery process. Patients may benefit from this research as it aims to improve the development of targeted therapies that are more effective and have fewer side effects. The project will validate its methods using specific human receptors and expand to include a broader range of GPCRs in later phases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that could be treated by therapies targeting GPCRs.
Not a fit: Patients with conditions unrelated to GPCR signaling may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective and targeted therapies for various diseases.
How similar studies have performed: Other research has shown success with similar multiplexed assay approaches, indicating potential for impactful advancements in drug discovery.
Where this research is happening
PITTSBURGH, UNITED STATES
- SPECTRAGENETICS — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ASBURY, G. REID — SPECTRAGENETICS
- Study coordinator: ASBURY, G. REID
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.