A new approach to tackle cancer drug resistance
A novel strategy to overcome drug resistance in cancer
This study is exploring new ways to fight cancer by looking at how some cancer cells resist treatment, and it aims to develop better therapies using natural compounds that can tackle multiple issues at once, which could help patients get more effective and lasting results.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-11042266 on NIH RePORTER |
What this research studies
This research investigates innovative strategies to combat the challenge of drug resistance in cancer treatment. By utilizing advanced techniques like single-cell sequencing, the study aims to understand the genetic diversity within tumors that allows some cancer cells to survive therapies. The approach focuses on leveraging natural compounds that can target multiple pathways simultaneously, potentially leading to more effective and long-lasting cancer treatments. Patients may benefit from therapies that are designed to be more robust against the development of resistance.
Who could benefit from this research
Good fit: Ideal candidates for this research include cancer patients who have experienced drug resistance or have not responded to standard therapies.
Not a fit: Patients with early-stage cancer who have not yet undergone treatment may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective cancer treatments that prevent or overcome drug resistance.
How similar studies have performed: Other research has shown promise in using multi-targeted approaches to overcome drug resistance, indicating that this strategy may be viable.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Edinger, Aimee L — University of California-Irvine
- Study coordinator: Edinger, Aimee L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.