NIH-funded research Sbir 2 grant

A new approach to personalized treatment for obesity

Official title: A NOVEL PRECISION MEDICINE APPROACH FOR OBESITY: A RANDOMIZED, MULTI-CENTER TRIAL

Funded at Phenomix Sciences, LLC · NIH-11056890 · Data updated 2026-11-12

This study is looking to help people with obesity lose weight more effectively by figuring out which factors influence how well anti-obesity medications work for them, so they can create personalized weight-loss plans just for you!

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionPhenomix Sciences, LLC
NIH-funded
Lab location1 site (Menlo Park, UNITED STATES)
Project startMarch 15, 2024
Project endFebruary 28, 2027
Funding year2025
Award (this year)$995,866
NIH project number5R44DK138619-02
Project IDNIH-11056890 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 21 and older who are struggling with obesity and seeking effective weight loss solutions.

Less likely to help

Patients who are not overweight or obese, or those who do not meet the age criteria, may not benefit from this research.

What this research studies

This research investigates how to improve weight loss outcomes for individuals with obesity by identifying predictors of response to anti-obesity medications (AOMs). The study will involve a randomized, multi-center trial that aims to develop individualized weight-loss strategies based on patient characteristics. By phenotyping participants, the research seeks to understand the variability in weight loss responses and enhance the effectiveness of treatments. Patients will be monitored for their weight loss progress and any side effects from the medications.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized obesity treatments, improving weight loss outcomes for patients.

How similar studies have gone: Other research has shown promise in identifying predictors of response to obesity treatments, suggesting that this approach could yield significant insights.

Where this research is happening

  • Phenomix Sciences, LLC
    Menlo Park, United States
    Active

Researchers

  • Principal investigator: Bagnall, Mark — Phenomix Sciences, LLC
  • Study coordinator: Bagnall, Mark

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.