A new adhesive for better fixing of cranial flaps after surgery
A Pilot Clinical Study for a Novel Bioresorbable Bone Adhesive to Evidence Improved Cranial Flap Fixation Based on Radiographic Imaging and Patient Reported Outcomes
This study is testing a new glue called Tetranite® that helps hold the pieces of your skull together after brain surgery, making it easier for you to heal and feel better, and it's for patients who have had a craniotomy.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Revbio, INC. NIH-funded |
| Lab location | 1 site (Lowell, UNITED STATES) |
| Project ID | NIH-10919591 on NIH RePORTER |
What this research studies
This research investigates a novel bioresorbable bone adhesive designed to improve the fixation of cranial flaps following craniotomy surgeries. The adhesive, called Tetranite®, is injected into the gaps left by the surgical procedure, aiming to create a strong bond that enhances healing and reduces complications such as loose plates or infections. By utilizing advanced imaging techniques and collecting patient-reported outcomes, the study will assess the effectiveness of this new adhesive compared to traditional methods. Patients participating in this research may experience improved recovery and reduced discomfort.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals scheduled to undergo craniotomy procedures requiring cranial flap closure.
Not a fit: Patients who have already undergone cranial flap closure using traditional methods and are not undergoing further surgeries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective cranial flap closures, reducing complications and improving patient satisfaction.
How similar studies have performed: While traditional methods have been widely used, this approach with a novel bioresorbable adhesive is relatively new and has not been extensively tested in clinical settings.
Where this research is happening
Lowell, UNITED STATES
- Revbio, INC. — Lowell, United States (Active)
Researchers
- Principal investigator: Hess, Brian — Revbio, INC.
- Study coordinator: Hess, Brian
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.