A new 3D printed device for delivering progesterone to help with infertility
Official title: Innovative 3D Printed Intravaginal Ring AnelleO-PRO, the first Single Administration of Progesterone for Infertility
Funded at Anelleo, INC. · NIH-10932305 · Data updated 2026-11-12
This study is testing a new 3D printed ring that releases progesterone over 28 days to help women going through fertility treatments like IVF, making it easier and more convenient for them to get the hormones they need.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Anelleo, INC. NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | September 21, 2019 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $1,389,051 |
| NIH project number | 5R44HD100190-05 |
| Project ID | NIH-10932305 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women of reproductive age who are experiencing infertility and are undergoing assisted reproductive technology treatments.
✕Less likely to help
Patients who are not seeking fertility treatments or who have contraindications to progesterone therapy may not benefit from this research.
What this research studies
This research focuses on developing a 3D printed intravaginal ring called AnelleO-PRO, designed to deliver progesterone over a 28-day period to support women undergoing assisted reproductive technology (ART) like in vitro fertilization (IVF). The device aims to improve patient compliance by providing a more convenient and effective method of hormone delivery compared to traditional options such as gels or injections. By utilizing advanced 3D printing technology, the ring can be produced quickly and cost-effectively, ensuring a steady release of progesterone throughout the critical early stages of pregnancy. This innovative approach addresses the common challenges faced by patients in maintaining adequate hormone levels during ART treatments.
Why it matters
Potential benefit: If successful, this research could significantly improve the chances of pregnancy for women undergoing fertility treatments by providing a more effective and user-friendly method of hormone supplementation.
How similar studies have gone: Previous research has shown promise in using intravaginal rings for hormone delivery, making this approach a potentially successful advancement in fertility treatment.
Where this research is happening
-
Anelleo, INC.
Chapel Hill, United States Active
Researchers
- Principal investigator: Janusziewicz, Rima — Anelleo, INC.
- Study coordinator: Janusziewicz, Rima
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.