A network to diagnose rare diseases in children in Southern California

Southern California Undiagnosed Disease Network

NIH-funded research University of California-Irvine · NIH-10979427

This study is working to help kids with rare diseases get the right diagnosis faster by teaming up with experts and local health partners, so they can receive the care they need.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine NIH-funded
Lab location1 site (Irvine, United States)
Project IDNIH-10979427 on NIH RePORTER

What this research studies

This research aims to improve the diagnosis of rare diseases in children by leveraging the expertise of UC Irvine and Children's Hospital of Orange County. It focuses on providing comprehensive evaluations for patients with undiagnosed conditions, utilizing advanced clinical testing and data science. The project will create a regional hub that collaborates with community health partners to serve medically underserved populations, ensuring that patients receive timely and accurate diagnoses. By collecting detailed genetic and phenotypic data, the initiative seeks to enhance understanding and treatment options for these complex conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years who are experiencing undiagnosed medical conditions.

Not a fit: Patients with well-defined diagnoses or those outside the age range of 0-11 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to faster and more accurate diagnoses for children with rare diseases, improving their quality of life.

How similar studies have performed: Similar initiatives have shown promise in improving diagnostic processes for rare diseases, indicating that this approach could be effective.

Where this research is happening

Irvine, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.