A network for improving care in critically ill children

Collaborative Pediatric Critical Care Research Network

NIH-funded research University of Utah · NIH-11160050

This study is working to improve treatments for seriously ill children with sepsis-related organ failure by bringing together hospitals to share information and develop personalized therapies that match each child's immune system, all while helping new doctors learn more about pediatric critical care.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Utah NIH-funded
Lab location1 site (Salt Lake City, United States)
Project IDNIH-11160050 on NIH RePORTER

What this research studies

This research focuses on enhancing treatment for critically ill children by establishing a collaborative network that conducts large-scale studies on immune modulation in cases of sepsis-induced multiple organ dysfunction syndrome. The project involves multiple clinical sites across diverse geographic and socioeconomic backgrounds, allowing for a comprehensive approach to understanding and treating this serious condition. By utilizing personalized, targeted therapies based on individual immune profiles, the research aims to improve patient outcomes significantly. The network also aims to foster the development of new clinician scientists in pediatric critical care.

Who could benefit from this research

Good fit: Ideal candidates for this research are critically ill children, particularly those under 21 years old, who are experiencing sepsis-induced multiple organ dysfunction syndrome.

Not a fit: Patients who are not critically ill or do not have sepsis-induced multiple organ dysfunction syndrome may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved survival rates and recovery outcomes for critically ill children suffering from sepsis.

How similar studies have performed: Previous studies have shown success in identifying immune phenotypes in critically ill children and reversing immunosuppression, indicating a promising foundation for this novel approach.

Where this research is happening

Salt Lake City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.