A network for improving care in critically ill children
Official title: Collaborative Pediatric Critical Care Research Network
Funded at University of Utah · NIH-11160050 · Data updated 2026-11-12
This study is working to improve treatments for seriously ill children with sepsis-related organ failure by bringing together hospitals to share information and develop personalized therapies that match each child's immune system, all while helping new doctors learn more about pediatric critical care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | August 13, 2021 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $150,000 |
| NIH project number | 3PL1HD105462-04S1 |
| Project ID | NIH-11160050 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are critically ill children, particularly those under 21 years old, who are experiencing sepsis-induced multiple organ dysfunction syndrome.
✕Less likely to help
Patients who are not critically ill or do not have sepsis-induced multiple organ dysfunction syndrome may not benefit from this research.
What this research studies
This research focuses on enhancing treatment for critically ill children by establishing a collaborative network that conducts large-scale studies on immune modulation in cases of sepsis-induced multiple organ dysfunction syndrome. The project involves multiple clinical sites across diverse geographic and socioeconomic backgrounds, allowing for a comprehensive approach to understanding and treating this serious condition. By utilizing personalized, targeted therapies based on individual immune profiles, the research aims to improve patient outcomes significantly. The network also aims to foster the development of new clinician scientists in pediatric critical care.
Why it matters
Potential benefit: If successful, this research could lead to improved survival rates and recovery outcomes for critically ill children suffering from sepsis.
How similar studies have gone: Previous studies have shown success in identifying immune phenotypes in critically ill children and reversing immunosuppression, indicating a promising foundation for this novel approach.
Where this research is happening
-
University of Utah
Salt Lake City, United States Active
Researchers
- Principal investigator: Watt, Kevin M — University of Utah
- Study coordinator: Watt, Kevin M
Related research
Other NIH-funded projects on the same topics.
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Collaborative Pediatric Critical Care Clinical Site (CPCCRN)
A nationwide network is testing personalized care approaches for seriously ill children with sepsis to improve outcomes.
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Collaborative Pediatric Critical Care Research Network: personalized care for septic kids
A nationwide network is testing personalized treatment approaches for children with sepsis-related organ failure to improve outcomes.
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Collaborative Pediatric Critical Care Network Site: Kids’ Sepsis Care
A pediatric-focused NIH grant supports a network site that helps tailor sepsis care for critically ill children across multiple centers.
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Personalized care for septic children through immunomodulation in MODS
This project tests a custom approach to treating pediatric sepsis in kids with organ failure by tailoring treatments to each child’s immune profile.
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Personalized immune-based care for septic kids with organ failure
A network study helps critically ill children with sepsis who have organ failure by tailoring treatments to their individual immune profiles.
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Collaborative Pediatric Critical Care Clinical Site for Precision Sepsis Care
A pediatric-focused research grant exploring personalized care for kids with severe sepsis to improve outcomes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.