A Nanodrug to Fight Metastatic Breast Cancer
anti-miR-10b Nanodrug for Treatment of Breast Cancer Metastasis: Study in Companion Animals
This research is exploring a new tiny drug delivery system to stop breast cancer from spreading in the body.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Michigan State University NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project ID | NIH-11124647 on NIH RePORTER |
What this research studies
Breast cancer that has spread to other parts of the body is very difficult to treat and is the main cause of death for patients. This research is developing a special "nanodrug" that can find and kill these spreading cancer cells. The nanodrug works by blocking a specific molecule, microRNA-10b, which metastatic cancer cells need to survive. Because these nanodrugs are magnetic, doctors could potentially use MRI scans to see where they go in the body, helping to guide treatment. This approach aims to bring advanced nanomedicine closer to helping patients.
Who could benefit from this research
Good fit: Patients with metastatic breast cancer, particularly those whose cancer has spread to areas like lymph nodes, lungs, bone, or brain, could potentially benefit from future treatments based on this research.
Not a fit: Patients with early-stage breast cancer that has not spread, or those with other types of cancer, may not directly benefit from this specific approach.
Why it matters
Potential benefit: If successful, this nanodrug could offer a new way to treat advanced breast cancer that has spread, potentially improving patient outcomes.
How similar studies have performed: Pre-clinical studies in mice and pilot studies in companion cats have shown promising results for delivering this nanodrug to established metastases.
Where this research is happening
East Lansing, United States
- Michigan State University — East Lansing, United States (Active)
Researchers
- Principal investigator: Moore, Anna — Michigan State University
- Study coordinator: Moore, Anna
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.