NIH-funded research R01 grant

A model to predict respiratory failure in COVID-19 patients

Official title: VentNet: A Real-Time Multimodal Data Integration Model for Prediction of Respiratory Failure in Patients with COVID-19

Funded at University of California, San Diego · NIH-11046630 · Data updated 2026-11-12

This study is creating a smart tool that uses health data to help doctors predict if COVID-19 patients might need breathing support within the next day, so they can act quickly and improve care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego
NIH-funded
Lab location1 site (La Jolla, United States)
Project startFebruary 15, 2022
Project endJanuary 31, 2026
Funding year2025
Award (this year)$651,706
NIH project number5R01HL157985-04
Project IDNIH-11046630 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are COVID-19 patients at risk of developing acute hypoxemic respiratory failure.

Less likely to help

Patients who are not infected with COVID-19 or those who do not exhibit risk factors for respiratory failure may not benefit from this research.

What this research studies

This research develops a predictive model using machine learning algorithms to analyze data from electronic health records (EHR) to forecast respiratory failure in COVID-19 patients 24 hours in advance. By integrating various clinical parameters, the model aims to improve decision-making for healthcare providers, helping them identify patients who may require mechanical ventilation sooner. This approach addresses the challenges faced during the pandemic, where timely intervention was critical for patient outcomes. The model has shown promising accuracy in preliminary tests, indicating its potential effectiveness in clinical settings.

Why it matters

Potential benefit: If successful, this research could significantly enhance the ability to predict respiratory failure, leading to timely interventions and improved patient outcomes.

How similar studies have gone: Other studies have successfully utilized machine learning for predictive modeling in healthcare, indicating a promising avenue for this approach.

Where this research is happening

  • University of California, San Diego
    La Jolla, United States
    Active

Researchers

  • Principal investigator: Nemati, Shamim — University of California, San Diego
  • Study coordinator: Nemati, Shamim

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.