A model to predict lymph node cancer spread for targeted radiation therapy
A Multifaceted Radiomics Model to Predict Cervical Lymph Node Metastasis for Involved Nodal Radiation Therapy
This study is looking to develop a smart tool that uses special imaging to figure out if lymph nodes in the neck have cancer, so that only the ones that really need treatment get targeted radiation, helping to avoid unnecessary side effects for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10873881 on NIH RePORTER |
What this research studies
This research aims to create a predictive model that uses advanced imaging techniques to determine whether lymph nodes in the neck are cancerous. By analyzing data from CT scans and other imaging modalities, the model will help identify which lymph nodes need targeted radiation therapy, potentially reducing unnecessary treatment of benign nodes. This approach seeks to minimize the side effects associated with radiation therapy, such as dry mouth and difficulty swallowing, by ensuring that only affected nodes are treated. Patients will be monitored closely to validate the model's effectiveness in real clinical settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with head and neck cancer who have lymph nodes that may be affected by the disease.
Not a fit: Patients with non-cancerous conditions or those whose lymph nodes are not involved in their cancer diagnosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more precise radiation therapy for head and neck cancer patients, reducing side effects and improving treatment outcomes.
How similar studies have performed: Previous research has shown promise in using imaging data for predicting cancer spread, suggesting that this approach could be effective.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Wang, Jing — Ut Southwestern Medical Center
- Study coordinator: Wang, Jing
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.