A model to help personalize re-irradiation treatment for patients
A generalizable model of normal tissue recovery to enable personalized re-irradiation
This study is looking at how healthy tissues heal after radiation treatment to help doctors make safer and more effective decisions about giving radiation again, so patients can get better care tailored to their needs.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10946838 on NIH RePORTER |
What this research studies
This research aims to develop a new framework for guiding re-irradiation treatments by analyzing how normal tissues recover from radiation damage. It addresses the current lack of data and guidelines in re-irradiation practices, which often vary widely and are not based on observed patient outcomes. By utilizing imaging techniques to monitor tissue recovery at specific follow-up intervals, the study seeks to create a more reliable approach to re-irradiation that can improve patient safety and treatment effectiveness. The goal is to provide clinicians with a better understanding of how to manage re-irradiation based on individual patient responses.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who have previously received radiation therapy and may require re-irradiation for their condition.
Not a fit: Patients who have never undergone radiation therapy or those with conditions not requiring re-irradiation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective re-irradiation treatments for patients who have previously undergone radiation therapy.
How similar studies have performed: Other research has shown promise in using imaging to assess tissue recovery, indicating that this approach may lead to significant advancements in re-irradiation practices.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Grassberger, Clemens — University of Washington
- Study coordinator: Grassberger, Clemens
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.