A model to help personalize re-irradiation treatment for patients
Official title: A generalizable model of normal tissue recovery to enable personalized re-irradiation
Funded at University of Washington · NIH-10946838 · Data updated 2026-11-12
This study is looking at how healthy tissues heal after radiation treatment to help doctors make safer and more effective decisions about giving radiation again, so patients can get better care tailored to their needs.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $399,829 |
| NIH project number | 1R21CA292207-01 |
| Project ID | NIH-10946838 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who have previously received radiation therapy and may require re-irradiation for their condition.
✕Less likely to help
Patients who have never undergone radiation therapy or those with conditions not requiring re-irradiation may not benefit from this research.
What this research studies
This research aims to develop a new framework for guiding re-irradiation treatments by analyzing how normal tissues recover from radiation damage. It addresses the current lack of data and guidelines in re-irradiation practices, which often vary widely and are not based on observed patient outcomes. By utilizing imaging techniques to monitor tissue recovery at specific follow-up intervals, the study seeks to create a more reliable approach to re-irradiation that can improve patient safety and treatment effectiveness. The goal is to provide clinicians with a better understanding of how to manage re-irradiation based on individual patient responses.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective re-irradiation treatments for patients who have previously undergone radiation therapy.
How similar studies have gone: Other research has shown promise in using imaging to assess tissue recovery, indicating that this approach may lead to significant advancements in re-irradiation practices.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Grassberger, Clemens — University of Washington
- Study coordinator: Grassberger, Clemens
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.