A mobile health program to help African women in sex work adhere to HIV treatment

Hybrid Type-1 Effectiveness-Implementation Trial of Motivation Matters! A Theory-Based mHealth Intervention to Support Early Antiretroviral Adherence in HIV+ African Women Who Engage in Sex Work

NIH-funded research University of Washington · NIH-10849520

This study is testing a friendly mobile program called Motivation Matters! to help African women who do sex work and are living with HIV stick to their medication, making sure it fits their needs and is easy to use.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Washington NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-10849520 on NIH RePORTER

What this research studies

This research focuses on developing and testing a mobile health intervention called Motivation Matters! (MM!) aimed at improving adherence to antiretroviral therapy (ART) among African women who engage in sex work and are living with HIV. The program is designed based on the Theory of Information, Motivation, and Behavior, and involves collaboration with the target population to ensure it meets their needs. Participants will receive support through an interactive platform that encourages adherence to their treatment regimen. The study aims to gather data on the effectiveness and acceptability of this intervention in a real-world setting.

Who could benefit from this research

Good fit: Ideal candidates for this research are African women who engage in sex work and are living with HIV.

Not a fit: Patients who are not engaged in sex work or are not living with HIV may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve ART adherence and health outcomes for HIV-positive women in sex work.

How similar studies have performed: Previous interventions targeting ART adherence in similar populations have shown limited success, highlighting the need for innovative approaches like MM!

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.