A mobile app to help manage childhood nephrotic syndrome
Official title: A Novel Mobile Application for Childhood Nephrotic Syndrome Management
Funded at Emory University · NIH-10655360 · Data updated 2026-11-12
This study is testing a helpful mobile app called UrApp that aims to support families in managing childhood nephrotic syndrome, making it easier for caregivers to take care of their kids with this kidney condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | September 1, 2019 |
| Project end | June 30, 2025 |
| Funding year | 2023 |
| Award (this year) | $183,531 |
| NIH project number | 5K23DK118189-05 |
| Project ID | NIH-10655360 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who have been newly diagnosed with nephrotic syndrome and their caregivers.
✕Less likely to help
Patients who are older than 11 years or those who do not have a diagnosis of nephrotic syndrome may not benefit from this research.
What this research studies
This research focuses on developing and testing a user-friendly mobile application designed to assist families in managing childhood nephrotic syndrome, a common chronic kidney disease in children. The app, named UrApp, aims to improve self-management and clinical outcomes by providing resources and support for caregivers of children with this condition. The research will involve a pilot randomized trial across three pediatric sites to evaluate the app's effectiveness in enhancing both behavioral and biological outcomes. Additionally, the study will assess factors that influence the app's effectiveness and engage caregivers to ensure the app meets their needs.
Why it matters
Potential benefit: If successful, this research could significantly improve the management of childhood nephrotic syndrome, leading to better health outcomes for affected children.
How similar studies have gone: Other research has shown success with mobile health applications in managing chronic diseases, indicating that this approach has potential for positive outcomes.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Wang, Chia-Shi — Emory University
- Study coordinator: Wang, Chia-Shi
Related research
Other NIH-funded projects on the same topics.
-
Whole genome sequencing to uncover molecular causes in nephrotic syndrome
A study to map the genetic and molecular factors behind nephrotic syndrome and related kidney diseases to help diagnose and guide future treatments for patients.
-
Sodium-related edema in nephrotic syndrome and ANGPTL4
A physician-scientist group is studying how a protein called ANGPTL4 may drive skin edema in nephrotic syndrome, with experiments in rodents and tests on human ANGPTL4 fragments.
-
Immune-driven tubulointerstitial injury in pediatric nephrotic syndrome
A physician-scientist aims to understand how immune processes cause kidney tissue damage in children with difficult-to-treat nephrotic syndrome.
-
Hodgkin lymphoma–linked nephrotic syndrome and kidney injury
This project looks at how Hodgkin lymphoma may cause nephrotic syndrome by changing a kidney gene and exposing kidney cells to lymphoma-related substances.
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Targeting calcineurin regulators for better diagnostics and treatments for nephrotic syndrome
This work looks at whether proteins that control calcineurin can be used to make better tests and more precise treatments for people with nephrotic syndrome.
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Investigating the role of a specific protein in childhood kidney disease
This study is looking at how a protein called CD93 might affect kidney health in children with Idiopathic Nephrotic Syndrome, and by examining blood and urine samples, researchers hope to find clues that could help doctors better understand and treat this condition.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.