A method for delivering gene-editing materials into cells without contact
High-Precision Non-Contact Plasmon-Induced Intracellular Delivery
This study is exploring a new way to safely and effectively deliver gene-editing tools into cells, especially stem cells, which could help treat conditions like cancer and genetic disorders.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10661807 on NIH RePORTER |
What this research studies
This research focuses on developing a new technique for delivering gene-editing materials into cells using plasmonic nanopipettes, which create localized electromagnetic fields. The goal is to enhance the efficiency and safety of gene delivery, particularly for stem cells, by overcoming current limitations of existing methods. By utilizing advanced technologies, the researchers aim to create a platform that can deliver various types of genetic materials into different cell types effectively. This approach could potentially allow for the treatment of a range of conditions, including cancers and genetic disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals with genetic disorders or cancers that could benefit from advanced gene-editing therapies.
Not a fit: Patients with conditions that do not involve genetic components or those who are not candidates for gene therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective gene therapies for various diseases, improving patient outcomes.
How similar studies have performed: Other research has shown promise in using similar plasmonic techniques for intracellular delivery, indicating potential for success in this novel approach.
Where this research is happening
Houston, United States
- University of Houston — Houston, United States (Active)
Researchers
- Principal investigator: Chiang, Naihao — University of Houston
- Study coordinator: Chiang, Naihao
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.