A long-lasting implant for contraception and HIV prevention
Long-acting multi prevention implant for 2-year contraception and HIV PrEP
['FUNDING_R01'] · METHODIST HOSPITAL RESEARCH INSTITUTE · NIH-11076310
This study is testing a new implant that helps women prevent both pregnancy and HIV for up to two years without needing to take daily pills, making it easier and more discreet for those at risk.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | METHODIST HOSPITAL RESEARCH INSTITUTE (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-11076310 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a long-acting implant that provides both contraception and HIV prevention for women. The implant will release two medications, etonogestrel and islatravir, over a two-year period, eliminating the need for daily adherence to pills. By using a novel delivery system that allows for discreet administration, the goal is to improve access and adherence to these critical health interventions, particularly in regions heavily affected by HIV. This approach aims to reduce unintended pregnancies and the risk of HIV infection among at-risk women.
Who could benefit from this research
Good fit: Ideal candidates for this research are sexually active women of childbearing age who are at risk for unintended pregnancies and HIV.
Not a fit: Patients who are not sexually active or those who do not require contraception or HIV prevention may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce maternal mortality and the incidence of HIV among women of childbearing age.
How similar studies have performed: Previous research has shown promise in developing multipurpose prevention technologies, but this specific approach using a long-acting implant is innovative and largely untested.
Where this research is happening
HOUSTON, UNITED STATES
- METHODIST HOSPITAL RESEARCH INSTITUTE — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GRATTONI, ALESSANDRO — METHODIST HOSPITAL RESEARCH INSTITUTE
- Study coordinator: GRATTONI, ALESSANDRO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome, Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome, Acquired Immunodeficiency Syndrome Virus