A global initiative to understand Parkinson's disease better

ENIGMA Parkinson’s Initiative: A Global Initiative for Parkinson’s Disease

NIH-funded research University of Southern California · NIH-10916343

This study is looking at how Parkinson's disease affects the brain by using special imaging techniques, and it's inviting people with Parkinson's from around the world to help us understand the disease better and find ways to track its progression.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Southern California NIH-funded
Lab location1 site (Los Angeles, UNITED STATES)
Project IDNIH-10916343 on NIH RePORTER

What this research studies

This research focuses on Parkinson's disease, a progressive neurodegenerative condition affecting millions worldwide. By utilizing advanced brain imaging techniques, the study aims to identify objective metrics that can gauge the progression of the disease and its impact on brain structures. The initiative seeks to gather data from a diverse, global population to enhance the understanding of Parkinson's and improve the reproducibility of findings. Patients will be involved in a coordinated effort to analyze brain imaging data and identify factors influencing disease severity.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with Parkinson's disease, particularly those in diverse geographic locations.

Not a fit: Patients with other neurodegenerative diseases or those without a Parkinson's diagnosis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for Parkinson's disease.

How similar studies have performed: Previous ENIGMA initiatives have successfully utilized a similar global consortium approach to study other mental health conditions, indicating a promising potential for this research.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.