A game to help older adults with cancer manage nausea and vomiting from chemotherapy

Serious gaming for chemotherapy-induced nausea and vomiting in older adults with cancer: A randomized clinical trial

NIH-funded research University of Central Florida · NIH-11120850

This project explores if a special computer game can help older adults with cancer feel better and manage nausea and vomiting after chemotherapy.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Central Florida NIH-funded
Lab location1 site (Orlando, United States)
Project IDNIH-11120850 on NIH RePORTER

What this research studies

Older adults with cancer often experience severe nausea and vomiting from chemotherapy, which they may not manage effectively, leading to reduced daily functioning and increased healthcare visits. This project introduces a 'serious game' called eSSET-CINV, an educational simulation designed to teach older adults how to prevent and manage these symptoms. Players interact with an avatar experiencing nausea after chemotherapy, making decisions to practice self-management strategies. The goal is to empower patients to take a more active role in managing their symptoms at home, potentially improving their quality of life.

Who could benefit from this research

Good fit: Ideal candidates are older adults, specifically those 65 years of age or older, who have cancer and are receiving chemotherapy.

Not a fit: Patients who are not receiving chemotherapy or are not older adults may not directly benefit from this specific intervention.

Why it matters

Potential benefit: If successful, this game could help older adults with cancer reduce their nausea and vomiting, improve their daily life, and potentially avoid emergency room visits.

How similar studies have performed: A preliminary study showed that older adults who used the eSSET-CINV intervention employed twice as many preventative strategies for nausea and vomiting, indicating promise for this approach.

Where this research is happening

Orlando, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.