NIH-funded research NIH-funded research

A family-engaged program to help people in South Africa stick with HIV treatment and opioid therapy

Official title: An intervention integrating peer navigation and family engagement to improve ART and OST adherence in South Africa

Funded at Arizona State University-Tempe Campus · NIH-11411426 · Data updated 2026-11-12

A team in South Africa is testing a support program that uses peer navigators and family involvement to help people who inject drugs stay on HIV treatment and opioid substitution therapy.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionArizona State University-Tempe Campus
NIH-funded
Lab location1 site (Scottsdale, United States)
Project startSeptember 30, 2024
Project endAugust 31, 2027
Funding year2026
Award (this year)$85,262
NIH project number5R34DA062367-03
Project IDNIH-11411426 on NIH RePORTER

Who could benefit from this research

Could help

Adults with HIV who inject drugs and receive ART and/or OST in the Yeoville Clinic setting or similar urban clinics in South Africa.

Less likely to help

Patients not currently engaged in ART/OST or lacking family support may see limited benefits from this approach.

What this research studies

This project builds on an existing ART and OST program in Johannesburg and adds training for peer navigators and a family-engagement component. It aims to see if involving family members improves 12-month ART/OST adherence and viral suppression among people who inject drugs living with HIV. The study plans to assemble evidence-based practices and test their preliminary impact in real-world clinic settings. It will measure adherence, retention, and related outcomes to guide future improvements. The work will be conducted with community partners and clinic staff to ensure relevance and feasibility in this setting.

Why it matters

Potential benefit: If successful, the program could help more people stay on HIV treatment and reduce transmission risk by improving adherence.

How similar studies have gone: Previous studies suggest peer navigation helps retention, but family-engaged approaches are emerging and feasibility remains to be proven.

Where this research is happening

  • Arizona State University-Tempe Campus
    Scottsdale, United States
    Active

Researchers

  • Principal investigator: Daniels, Joseph — Arizona State University-Tempe Campus
  • Study coordinator: Daniels, Joseph

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.