A facility for advanced DNA sequencing techniques
Official title: Next Generation Sequencing Core
Funded at University of Pennsylvania · NIH-10914931 · Data updated 2026-11-12
This study is setting up a special lab that uses advanced DNA sequencing techniques to help researchers learn more about the genetic causes of diseases, which could ultimately benefit patients like you.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $424,496 |
| NIH project number | 5P01CA281867-02 |
| Project ID | NIH-10914931 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with genetic conditions or cancers that may be influenced by chromatin accessibility and gene expression.
✕Less likely to help
Patients with conditions unrelated to genetic factors or those not requiring advanced genomic analysis may not receive benefit from this research.
What this research studies
This research focuses on establishing a core facility for next-generation sequencing (NGS) that will support various projects by performing advanced sequencing techniques such as RNA-Seq, ChIP-Seq, and ATAC-Seq. The facility will generate libraries for sequencing, map sequence data to various genomes, and provide comprehensive bioinformatics and biostatistics analyses. Patients may benefit from the insights gained through this sequencing, which can enhance understanding of genetic factors in diseases. The facility will be managed by experienced leaders in the field to ensure high-quality results.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of genetic contributions to diseases, potentially informing better treatment strategies.
How similar studies have gone: Previous research utilizing next-generation sequencing techniques has shown significant success in advancing our understanding of genetic diseases and informing treatment options.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Robertson, Erle S. — University of Pennsylvania
- Study coordinator: Robertson, Erle S.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.