A facility for advanced DNA sequencing techniques

Next Generation Sequencing Core

['FUNDING_P01'] · UNIVERSITY OF PENNSYLVANIA · NIH-10914931

This study is setting up a special lab that uses advanced DNA sequencing techniques to help researchers learn more about the genetic causes of diseases, which could ultimately benefit patients like you.

Quick facts

Phase['FUNDING_P01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PENNSYLVANIA (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-10914931 on ClinicalTrials.gov

What this research studies

This research focuses on establishing a core facility for next-generation sequencing (NGS) that will support various projects by performing advanced sequencing techniques such as RNA-Seq, ChIP-Seq, and ATAC-Seq. The facility will generate libraries for sequencing, map sequence data to various genomes, and provide comprehensive bioinformatics and biostatistics analyses. Patients may benefit from the insights gained through this sequencing, which can enhance understanding of genetic factors in diseases. The facility will be managed by experienced leaders in the field to ensure high-quality results.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research include individuals with genetic conditions or cancers that may be influenced by chromatin accessibility and gene expression.

Not a fit: Patients with conditions unrelated to genetic factors or those not requiring advanced genomic analysis may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding of genetic contributions to diseases, potentially informing better treatment strategies.

How similar studies have performed: Previous research utilizing next-generation sequencing techniques has shown significant success in advancing our understanding of genetic diseases and informing treatment options.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.