A diverse Alzheimer's genetics resource for African and Hispanic ancestry communities
Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)
This project will enroll people of African and Hispanic ancestry to collect health information and DNA so we can better understand Alzheimer's risk in those communities.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-11380131 on NIH RePORTER |
What this research studies
You may be invited to join a large effort that aims to include people of African and Hispanic genetic ancestry who have, or are at risk for, Alzheimer's disease. Participants will be asked to share basic health and demographic information, undergo brief cognitive or health assessments, and provide a blood or saliva sample for DNA testing. The project plans to recruit and genotype about 13,000 people and will use community-sensitive outreach to build trust and improve participation. Results will be combined into a shared research resource to help researchers study genetic risk factors that have been underrepresented to date.
Who could benefit from this research
Good fit: Adults of African or Hispanic genetic ancestry, with or without Alzheimer's symptoms, who are willing to provide health information and a blood or saliva sample are ideal candidates.
Not a fit: People who are not of African or Hispanic genetic ancestry or those expecting immediate changes to their medical care are unlikely to receive direct personal benefit from participation.
Why it matters
Potential benefit: If successful, this work could improve genetic risk information and lead to better diagnosis and treatments tailored to people of African and Hispanic ancestry.
How similar studies have performed: Large genetics studies in European-ancestry groups have identified Alzheimer-related genes, and smaller studies in African American groups have found different risk signals, but larger diverse cohorts are still needed.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Pericak-Vance, Margaret a. — University of Miami School of Medicine
- Study coordinator: Pericak-Vance, Margaret a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.