A digital program to help older adults with obesity and depression

digital InteGrated behavioral treatmeNt for comorbid obesITy and deprEssion among racial and ethnic adults age 50 and older (IGNITE)

NIH-funded research University of Illinois at Chicago · NIH-11040989

This study is testing a friendly voice coach on Amazon's Alexa that helps older adults, especially those from different racial and ethnic backgrounds, tackle both obesity and depression at the same time, making it easier for them to stick to their treatment and feel better overall.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Chicago NIH-funded
Lab location1 site (Chicago, UNITED STATES)
Project IDNIH-11040989 on NIH RePORTER

What this research studies

This research investigates a digital behavioral intervention designed to address both obesity and depression in older adults, particularly focusing on racial and ethnic minorities. The program utilizes a voice-based virtual coach on Amazon's Alexa platform to deliver integrated treatment, combining problem-solving therapy for depression with a behavioral weight loss intervention. By targeting both conditions simultaneously, the research aims to improve treatment adherence and quality of life for participants. The approach is designed to be scalable and accessible, addressing the unique challenges faced by older adults in managing these comorbid conditions.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 50 and older who are experiencing both obesity and depression, particularly those from racial and ethnic minority backgrounds.

Not a fit: Patients who do not have obesity or depression, or those under the age of 50, may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the mental and physical health of older adults suffering from both obesity and depression.

How similar studies have performed: Previous research has shown success with integrated behavioral interventions for comorbid conditions, indicating a promising approach for this novel digital intervention.

Where this research is happening

Chicago, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.