A dietary intervention to reduce inflammation in chronic pancreatitis
Official title: A dietary intervention clinical trial to reduce inflammation and improve outcomes in chronic pancreatitis
Funded at Ohio State University · NIH-11049683 · Data updated 2026-11-12
This study is looking at how drinking soy-tomato juice might help reduce inflammation and improve health for people with chronic pancreatitis, and we're inviting participants to try it out and see how it affects their overall well-being.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | January 20, 2025 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $306,994 |
| NIH project number | 1R01DK138871-01A1 |
| Project ID | NIH-11049683 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with chronic pancreatitis who are experiencing inflammation-related complications.
✕Less likely to help
Patients who do not have chronic pancreatitis or those with acute pancreatitis may not benefit from this research.
What this research studies
This research investigates the effects of a soy-tomato juice dietary intervention on reducing inflammation and improving health outcomes in patients with chronic pancreatitis. The study aims to explore how this novel dietary approach can influence immune responses and metabolic complications associated with the condition. Participants will consume the soy-tomato juice, and researchers will monitor changes in inflammatory markers and overall health. The goal is to provide a non-invasive treatment option that addresses the underlying inflammation in chronic pancreatitis.
Why it matters
Potential benefit: If successful, this research could offer a new dietary treatment to help manage inflammation and improve the quality of life for patients with chronic pancreatitis.
How similar studies have gone: Previous studies have shown that dietary interventions can effectively reduce inflammation in other chronic conditions, suggesting potential success for this approach in chronic pancreatitis.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Mace, Thomas a — Ohio State University
- Study coordinator: Mace, Thomas a
Related research
Other NIH-funded projects on the same topics.
-
Chronic Pancreatitis and Related Conditions Data Center Supports Multi-Center Research
A national effort to organize and share clinical data and biosamples from people with chronic pancreatitis, pancreatogenic diabetes, and pancreatic cancer to speed biomarker discovery and new treatments.
-
Malabsorption Blood Test for Exocrine Pancreatic Function in Chronic Pancreatitis
A blood test (MBT) will help identify people with mild to moderate pancreatic fat malabsorption and show how well enzyme therapy improves their quality of life.
-
Chronic Pancreatitis Clinical Research Cohort and Biorepository
A long-term study at UF/Advent Health following adults with acute, relapsing, and chronic pancreatitis to build a detailed group with biospecimens and data for better diagnosis and personalized care.
-
Cedars-Sinai Center leads research on chronic pancreatitis and pancreatic cancer
A Cedars-Sinai research center is renewing its program to study chronic pancreatitis, diabetes-related pancreatic disease, and pancreatic cancer so doctors can better understand and treat these conditions.
-
UPMC Center for Pancreatitis and Diabetes research program
A specialized center at the University of Pittsburgh is advancing clinical and biological studies of chronic pancreatitis, recurrent acute pancreatitis, and diabetes to improve understanding and care.
-
Chronic Pancreatitis Research Network to Understand Symptoms and Find Treatments
This project advances studies of chronic pancreatitis to understand why some people progress and to test new ideas that could diagnose or slow the disease.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.