A diet with reduced carbohydrates to improve liver health in adolescents with fatty liver disease
Moderately CHO-restricted diet as treatment targeting improvement in hepatic lipid and insulin sensitivity in adolescents with NAFLD
This study is looking at how a diet with fewer carbohydrates can help teenagers with non-alcoholic fatty liver disease improve their liver health and insulin sensitivity, making it easier for them to avoid more serious health issues later on.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-11109565 on NIH RePORTER |
What this research studies
This research investigates the effects of a moderately carbohydrate-restricted diet on adolescents suffering from non-alcoholic fatty liver disease (NAFLD). The study aims to determine if this dietary approach can improve liver lipid levels and insulin sensitivity, which are critical for preventing the progression of NAFLD to more severe liver conditions and related diseases like type 2 diabetes. Participants will be guided through dietary changes and monitored for improvements in their liver health and metabolic function. The research seeks to establish evidence-based dietary guidelines for managing NAFLD in young patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents diagnosed with non-alcoholic fatty liver disease (NAFLD).
Not a fit: Patients who do not have NAFLD or those with advanced liver disease requiring immediate medical intervention may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a non-pharmaceutical dietary intervention to effectively reverse NAFLD and prevent its progression in adolescents.
How similar studies have performed: Previous research has shown promising results with dietary interventions in managing NAFLD, indicating that this approach may be effective.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Goss, Amy Miskimon — University of Alabama at Birmingham
- Study coordinator: Goss, Amy Miskimon
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.