A diet tailored to specific allergens for treating eosinophilic esophagitis.
An allergen-specific immune signature-directed diet vs sham diet for treatment of eosinophilic esophagitis: A pilot-feasibility study
This study is looking at how a personalized diet can help people with eosinophilic esophagitis (EoE) by figuring out which specific foods trigger their symptoms, so they can avoid those foods without the hassle of a strict elimination diet.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10817001 on NIH RePORTER |
What this research studies
This research investigates a personalized diet based on individual immune responses to allergens in patients with eosinophilic esophagitis (EoE). It aims to replace the current one-size-fits-all dietary elimination approach, which can be burdensome and ineffective. By identifying specific food triggers through advanced testing, the study seeks to streamline dietary management, making it less invasive and more effective for patients. Participants will be monitored to assess the impact of the tailored diet on their symptoms and overall health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with eosinophilic esophagitis who are struggling with dietary management of their condition.
Not a fit: Patients who do not have eosinophilic esophagitis or those whose condition is not related to food allergies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective dietary treatments for eosinophilic esophagitis, improving patients' quality of life.
How similar studies have performed: Previous research has shown promise in using personalized dietary approaches for food allergies, suggesting potential success for this novel method in treating eosinophilic esophagitis.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Dellon, Evan Samuel — Univ of North Carolina Chapel Hill
- Study coordinator: Dellon, Evan Samuel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.