A device to relieve pressure in the heart for treating congestive heart failure.
Official title: Transcatheter Device for Congestive Heart Failure Treatment Through Left Atrial Decompression
Funded at Alleviant Medical, INC. · NIH-11011326 · Data updated 2026-11-12
This study is testing a new device that helps relieve symptoms of congestive heart failure by improving blood flow in the heart, and it's designed for patients with this condition who might benefit from a fresh treatment option.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Alleviant Medical, INC. NIH-funded |
| Lab location | 1 site (Austin, UNITED STATES) |
| Project start | September 1, 2018 |
| Project end | February 28, 2027 |
| Funding year | 2025 |
| Award (this year) | $992,964 |
| NIH project number | 5R44HL142440-05 |
| Project ID | NIH-11011326 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with congestive heart failure, particularly those with preserved or mid-range ejection fraction.
✕Less likely to help
Patients with heart failure who do not have elevated left atrial pressure or those with other underlying conditions that contraindicate the use of the device may not benefit from this research.
What this research studies
This research investigates a novel transcatheter device designed to alleviate symptoms of congestive heart failure (CHF) by decompressing the left atrium. The approach involves creating a connection between the high-pressure left atrium and the low-pressure right atrium, which may help lower elevated left atrial pressure and improve blood flow. Patients with CHF, particularly those with preserved ejection fraction, may benefit from this innovative treatment option. The study aims to assess the safety and effectiveness of this device in improving patient outcomes.
Why it matters
Potential benefit: If successful, this research could provide a new treatment option for patients suffering from congestive heart failure, potentially improving their quality of life and reducing hospitalizations.
How similar studies have gone: Other research has shown promise with similar interatrial shunting approaches, indicating potential for success in this novel treatment strategy.
Where this research is happening
-
Alleviant Medical, INC.
Austin, United States Active
Researchers
- Principal investigator: Pate, Thomas Diffley — Alleviant Medical, INC.
- Study coordinator: Pate, Thomas Diffley
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.