A device to relieve pain from migraines and headaches without drugs

Drug Free Nerve Block Device for the Relief of Pain and Symptoms in Migraines and other Headaches

NIH-funded research Thermaquil, INC. · NIH-10493404

This study is testing a new, easy-to-use device that helps people with migraines and headaches manage their pain without medication, and it's for anyone looking for a drug-free way to find relief.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionThermaquil, INC. NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10493404 on NIH RePORTER

What this research studies

This research investigates a novel, noninvasive device designed to provide pain relief for individuals suffering from migraines and other types of headaches. The device allows patients to control their pain management without the use of drugs, which can have significant side effects. The approach involves thermal neuromodulation, which has shown promising results in preliminary studies with patients who have not found relief from traditional treatments. Participants will undergo a 28-day assessment to track their headache frequency, intensity, and overall quality of life.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who experience frequent migraines or chronic headaches and have not found relief from existing treatments.

Not a fit: Patients who do not suffer from migraines or chronic headaches may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a safe and effective alternative for patients seeking relief from chronic headache pain without relying on medications.

How similar studies have performed: Preliminary studies have shown success with similar noninvasive approaches, indicating potential for this device to be effective.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.