A device to reduce the side effects of chemotherapy by filtering drugs from the bloodstream.
Endovascular ChemoFilter to Reduce Doxorubicin Toxicity during Intra-Arterial Chemotherapy
This study is testing a new device called the ChemoFilter that helps make chemotherapy safer for patients with liver tumors by removing extra chemotherapy drugs from the bloodstream during treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Filtro Medical INC. NIH-funded |
| Lab location | 1 site (San Jose, UNITED STATES) |
| Project ID | NIH-10930909 on NIH RePORTER |
What this research studies
This research focuses on developing a new medical device called a ChemoFilter, which is used during intra-arterial chemotherapy to selectively remove excess chemotherapy drugs from the bloodstream. By deploying this device in the veins draining the organ being treated, it aims to minimize systemic toxicity caused by these drugs. The ChemoFilter binds to the drugs in situ, allowing for safer and more effective cancer treatment. Patients undergoing chemotherapy for liver tumors may particularly benefit from this innovative approach.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients receiving intra-arterial chemotherapy for liver tumors.
Not a fit: Patients who are not undergoing intra-arterial chemotherapy or those with tumors in other locations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the harmful side effects of chemotherapy, improving patient quality of life during treatment.
How similar studies have performed: While the concept of drug filtration during chemotherapy is innovative, similar approaches have shown promise in preliminary studies, suggesting potential for success.
Where this research is happening
San Jose, UNITED STATES
- Filtro Medical INC. — San Jose, United States (Active)
Researchers
- Principal investigator: Hetts, Steven William — Filtro Medical INC.
- Study coordinator: Hetts, Steven William
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.