A device to prevent pregnancy and HIV using a combination of hormones and an anti-HIV agent
Official title: An Etonogestrel/Ethinyl Estradiol/QGriffithsin (ETG/EE/QGRFT) IVR to Prevent Pregnancy and HIV
Funded at Population Council · NIH-10798184 · Data updated 2026-11-12
This study is testing a new intravaginal ring that offers both birth control and protection against HIV for women, aiming to make it safer and more comfortable than current options.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Population Council NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | April 6, 2020 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $805,684 |
| NIH project number | 5R01AI150360-05 |
| Project ID | NIH-10798184 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are sexually active individuals at risk of unintended pregnancy and HIV infection.
✕Less likely to help
Patients who are not sexually active or those who do not require contraception or HIV prevention may not benefit from this research.
What this research studies
This research focuses on developing an innovative intravaginal ring (IVR) that combines the hormones etonogestrel and ethinyl estradiol with an anti-HIV agent called QGriffithsin. The device is designed to be used for 90 days, providing effective contraception while also preventing HIV transmission. The approach includes advanced formulation techniques to ensure the sustained release of the components, aiming to improve safety and reduce side effects compared to existing contraceptive methods. The research will also involve testing the safety and effectiveness of the IVR in animal models before moving to human trials.
Why it matters
Potential benefit: If successful, this research could provide a dual-purpose contraceptive method that effectively prevents both unintended pregnancies and HIV infection.
How similar studies have gone: Previous research has shown promise in developing multipurpose prevention technologies, indicating potential for success in this novel approach.
Where this research is happening
-
Population Council
New York, United States Active
Researchers
- Principal investigator: Teleshova, Natalia — Population Council
- Study coordinator: Teleshova, Natalia
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.