A device to predict severe acute kidney injury
A Device for Detection of Acute Kidney Injury
This study is working on a new device that can help doctors predict if patients are at risk of serious kidney problems by looking at certain proteins in their urine, making it easier to manage their care and improve their treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Nephsmart LLC NIH-funded |
| Lab location | 1 site (Little Rock, United States) |
| Project ID | NIH-10919989 on NIH RePORTER |
What this research studies
This research focuses on developing a device that can predict the risk of severe acute kidney injury (AKI) in patients. By analyzing specific protein cleavage patterns in urine, the device aims to differentiate between patients who will experience severe AKI and those who will not. The approach involves creating a point-of-care test that can provide timely predictions, potentially improving patient management and treatment outcomes. The research is based on preliminary findings that suggest this method could be both sensitive and specific in identifying at-risk patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients who are at risk of developing severe acute kidney injury, particularly those with mild to moderate AKI.
Not a fit: Patients with no history of kidney issues or those who are not at risk for acute kidney injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier interventions for patients at risk of severe acute kidney injury, potentially reducing the need for dialysis and improving overall kidney health.
How similar studies have performed: Other research has shown promise in using biomarkers for predicting kidney injury, but this specific approach utilizing protein cleavage is novel.
Where this research is happening
Little Rock, United States
- Nephsmart LLC — Little Rock, United States (Active)
Researchers
- Principal investigator: Arthur, John M. — Nephsmart LLC
- Study coordinator: Arthur, John M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.