A device to monitor disease progression in ALS

A Digital Biomarker for ALS - Pison Neural Biosensor

['FUNDING_SBIR_2'] · PISON TECHNOLOGY, INC. · NIH-11069980

This study is testing a new wearable device that helps people with ALS by continuously tracking their muscle signals, so they can get better care and treatment based on real-time information about their condition.

Quick facts

Phase['FUNDING_SBIR_2']
Study typeNih_funding
SexAll
SponsorPISON TECHNOLOGY, INC. (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-11069980 on ClinicalTrials.gov

What this research studies

This research focuses on developing a wearable device that continuously collects and analyzes neurological signals from patients with amyotrophic lateral sclerosis (ALS). The device uses surface electromyography (sEMG) technology to gather real-time data, which is then processed through cloud-based algorithms to create a digital biomarker for tracking disease progression. By enabling early identification and monitoring of ALS, this research aims to improve patient management and inform treatment decisions. The device is designed to be easily deployable, making it accessible for patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with amyotrophic lateral sclerosis (ALS) who are seeking innovative ways to monitor their condition.

Not a fit: Patients with other neurological disorders or those not diagnosed with ALS may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a reliable method for early detection and monitoring of ALS, potentially leading to better management of the disease.

How similar studies have performed: Previous research has shown promise in using wearable technology for monitoring neurological conditions, indicating that this approach may be effective for ALS as well.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Amyotrophic Lateral Sclerosis Motor Neuron Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.