A device to monitor disease progression in ALS
Official title: A Digital Biomarker for ALS - Pison Neural Biosensor
Funded at Pison Technology, INC. · NIH-11069980 · Data updated 2026-11-12
This study is testing a new wearable device that helps people with ALS by continuously tracking their muscle signals, so they can get better care and treatment based on real-time information about their condition.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pison Technology, INC. NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | June 12, 2025 |
| Project end | May 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $459,097 |
| NIH project number | 1R44NS137933-01A1 |
| Project ID | NIH-11069980 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with amyotrophic lateral sclerosis (ALS) who are seeking innovative ways to monitor their condition.
✕Less likely to help
Patients with other neurological disorders or those not diagnosed with ALS may not benefit from this research.
What this research studies
This research focuses on developing a wearable device that continuously collects and analyzes neurological signals from patients with amyotrophic lateral sclerosis (ALS). The device uses surface electromyography (sEMG) technology to gather real-time data, which is then processed through cloud-based algorithms to create a digital biomarker for tracking disease progression. By enabling early identification and monitoring of ALS, this research aims to improve patient management and inform treatment decisions. The device is designed to be easily deployable, making it accessible for patients.
Why it matters
Potential benefit: If successful, this research could provide a reliable method for early detection and monitoring of ALS, potentially leading to better management of the disease.
How similar studies have gone: Previous research has shown promise in using wearable technology for monitoring neurological conditions, indicating that this approach may be effective for ALS as well.
Where this research is happening
-
Pison Technology, INC.
Boston, United States Active
Researchers
- Principal investigator: Blackwell, Megan H — Pison Technology, INC.
- Study coordinator: Blackwell, Megan H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.