A device to measure brain chemicals in real-time
Official title: Implantable Microarray Probe for Real-Time Glutamate and GABA Detection
Funded at Alcorix · NIH-10930948 · Data updated 2026-11-12
This study is testing a new tiny device that can continuously check the levels of two important brain chemicals, glutamate and GABA, to help us better understand brain disorders like dementia and epilepsy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Alcorix NIH-funded |
| Lab location | 1 site (Plainfield, United States) |
| Project start | September 18, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $902,911 |
| NIH project number | 5R42NS115282-03 |
| Project ID | NIH-10930948 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research would include individuals affected by neurological disorders such as epilepsy, dementia, or Parkinson's disease.
✕Less likely to help
Patients with conditions unrelated to neurotransmitter imbalances or those not experiencing neurological disorders may not benefit from this research.
What this research studies
This research focuses on developing a novel implantable biosensor that can continuously and simultaneously detect two important neurotransmitters, glutamate and GABA, in real-time. These neurotransmitters play crucial roles in brain function, and their balance is vital for processes like memory and information processing. The device aims to provide insights into neurotransmitter dynamics, which could enhance our understanding of various brain disorders, including dementia and epilepsy. By using a small, flexible probe, the research seeks to improve the accuracy and efficiency of neurotransmitter measurement compared to existing methods.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for brain disorders related to neurotransmitter imbalances.
How similar studies have gone: While the approach of real-time neurotransmitter detection is innovative, similar technologies have shown promise in animal studies, indicating potential for success in human applications.
Where this research is happening
-
Alcorix
Plainfield, United States Active
Researchers
- Principal investigator: Moldovan, Nicolaie Andrei — Alcorix
- Study coordinator: Moldovan, Nicolaie Andrei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.