A device to measure brain chemicals in real-time
Implantable Microarray Probe for Real-Time Glutamate and GABA Detection
This study is testing a new tiny device that can continuously check the levels of two important brain chemicals, glutamate and GABA, to help us better understand brain disorders like dementia and epilepsy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Alcorix NIH-funded |
| Lab location | 1 site (Plainfield, United States) |
| Project ID | NIH-10930948 on NIH RePORTER |
What this research studies
This research focuses on developing a novel implantable biosensor that can continuously and simultaneously detect two important neurotransmitters, glutamate and GABA, in real-time. These neurotransmitters play crucial roles in brain function, and their balance is vital for processes like memory and information processing. The device aims to provide insights into neurotransmitter dynamics, which could enhance our understanding of various brain disorders, including dementia and epilepsy. By using a small, flexible probe, the research seeks to improve the accuracy and efficiency of neurotransmitter measurement compared to existing methods.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals affected by neurological disorders such as epilepsy, dementia, or Parkinson's disease.
Not a fit: Patients with conditions unrelated to neurotransmitter imbalances or those not experiencing neurological disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for brain disorders related to neurotransmitter imbalances.
How similar studies have performed: While the approach of real-time neurotransmitter detection is innovative, similar technologies have shown promise in animal studies, indicating potential for success in human applications.
Where this research is happening
Plainfield, United States
- Alcorix — Plainfield, United States (Active)
Researchers
- Principal investigator: Moldovan, Nicolaie Andrei — Alcorix
- Study coordinator: Moldovan, Nicolaie Andrei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.