A device to improve sleep for people with substance use disorder

Head-worn low intensity focused ultrasound (LIFU) device for enhancing sleep in substance use disorder (SUD)

NIH-funded research Attune Neurosciences, INC. · NIH-11069324

This study is testing a special headband that uses gentle ultrasound to help people with substance use disorder, especially those struggling with opioid use, get better sleep and feel less anxious about it.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionAttune Neurosciences, INC. NIH-funded
Lab location1 site (San Francisco, UNITED STATES)
Project IDNIH-11069324 on NIH RePORTER

What this research studies

This research investigates a head-worn low intensity focused ultrasound (LIFU) device designed to enhance sleep quality in individuals suffering from substance use disorder (SUD). The approach focuses on addressing the chronic sleep dysfunction that often accompanies SUD, particularly opioid use disorder (OUD), which can lead to relapse. By utilizing non-pharmacological methods, the device aims to improve sleep architecture and reduce anxiety related to sleep disturbances. Participants will be monitored for changes in sleep patterns and overall recovery outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with substance use disorder, particularly those experiencing sleep disturbances.

Not a fit: Patients who do not have substance use disorder or those without significant sleep issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve sleep quality for patients with substance use disorder, potentially reducing relapse rates.

How similar studies have performed: While the use of focused ultrasound for sleep enhancement is a novel approach, similar non-pharmacological interventions have shown promise in improving sleep quality in other populations.

Where this research is happening

San Francisco, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions addictive disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.