A device to help improve skull and jaw growth in babies with facial differences
Official title: A Smart, Fully Subcutaneous Distraction System to Improve Outcomes in Patients with Congenital or Acquired Craniofacial Differences
Funded at Ostiio LLC · NIH-10929326 · Data updated 2026-11-12
This study is testing a new device that helps babies with head shape differences grow their bones safely from inside their bodies, making recovery easier and reducing the chance of infections or scars.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ostiio LLC NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 14, 2023 |
| Project end | September 13, 2025 |
| Funding year | 2024 |
| Award (this year) | $849,999 |
| NIH project number | 5R44DE031195-03 |
| Project ID | NIH-10929326 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are newborns and infants diagnosed with congenital or acquired craniofacial conditions requiring surgical intervention.
✕Less likely to help
Patients with craniofacial differences who are older or have already undergone extensive surgical treatments may not benefit from this research.
What this research studies
This research focuses on developing a fully subcutaneous distraction system designed to enhance outcomes for infants with congenital or acquired craniofacial differences. The approach involves using a device that can gradually lengthen and reshape bone without the complications associated with external distractors, which are currently used in surgical treatments. By eliminating the external components, the research aims to reduce risks such as infection and scarring, ultimately improving the recovery experience for patients. The study will assess the effectiveness of this innovative device in promoting bone regeneration and correcting skeletal deficiencies.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective treatments for infants with craniofacial differences, improving their overall health and quality of life.
How similar studies have gone: While distraction osteogenesis has been used in various forms, this specific fully subcutaneous approach is novel and has not been extensively tested in clinical settings.
Where this research is happening
-
Ostiio LLC
Philadelphia, United States Active
Researchers
- Principal investigator: Desnoyer, Jessica — Ostiio LLC
- Study coordinator: Desnoyer, Jessica
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.