A device that automatically adjusts to treat sleep breathing problems.
Official title: Auto-Titrating Oral Appliance for Sleep Disordered Breathing
Funded at Rush River Research Corporation · NIH-10697976 · Data updated 2026-11-12
This study is testing a new, smart mouthpiece that automatically adjusts to help people with Sleep Disordered Breathing sleep better, making it easier and more comfortable to use than traditional treatments like CPAP.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rush River Research Corporation NIH-funded |
| Lab location | 1 site (Ellsworth, United States) |
| Project start | September 1, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $299,254 |
| NIH project number | 1R43HL166039-01A1 |
| Project ID | NIH-10697976 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Sleep Disordered Breathing who have difficulty using CPAP or are seeking alternative treatment options.
✕Less likely to help
Patients who do not have Sleep Disordered Breathing or those who are already successfully using CPAP may not benefit from this research.
What this research studies
This research focuses on developing an innovative oral appliance designed to treat Sleep Disordered Breathing (SDB) by automatically adjusting its fit and function. The device aims to improve patient compliance and comfort compared to traditional treatments like CPAP, which many patients find difficult to tolerate. By utilizing advanced sensing technology, the appliance will monitor the patient's breathing patterns and adjust accordingly, potentially reducing the need for multiple dental visits for titration. This approach seeks to provide a more effective and user-friendly solution for individuals suffering from airway obstruction during sleep.
Why it matters
Potential benefit: If successful, this research could lead to a more effective and comfortable treatment option for patients with sleep disordered breathing, potentially improving their overall health and quality of life.
How similar studies have gone: While there have been various approaches to treating SDB, the specific auto-titrating technology proposed in this research is relatively novel and has not been widely tested in this form.
Where this research is happening
-
Rush River Research Corporation
Ellsworth, United States Active
Researchers
- Principal investigator: Lundstrom, Julie — Rush River Research Corporation
- Study coordinator: Lundstrom, Julie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.