A device that automatically adjusts to treat sleep breathing problems.

Auto-Titrating Oral Appliance for Sleep Disordered Breathing

['FUNDING_SBIR_1'] · RUSH RIVER RESEARCH CORPORATION · NIH-10697976

This study is testing a new, smart mouthpiece that automatically adjusts to help people with Sleep Disordered Breathing sleep better, making it easier and more comfortable to use than traditional treatments like CPAP.

Quick facts

Phase['FUNDING_SBIR_1']
Study typeNih_funding
SexAll
SponsorRUSH RIVER RESEARCH CORPORATION (nih funded)
Locations1 site (ELLSWORTH, UNITED STATES)
Trial IDNIH-10697976 on ClinicalTrials.gov

What this research studies

This research focuses on developing an innovative oral appliance designed to treat Sleep Disordered Breathing (SDB) by automatically adjusting its fit and function. The device aims to improve patient compliance and comfort compared to traditional treatments like CPAP, which many patients find difficult to tolerate. By utilizing advanced sensing technology, the appliance will monitor the patient's breathing patterns and adjust accordingly, potentially reducing the need for multiple dental visits for titration. This approach seeks to provide a more effective and user-friendly solution for individuals suffering from airway obstruction during sleep.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Sleep Disordered Breathing who have difficulty using CPAP or are seeking alternative treatment options.

Not a fit: Patients who do not have Sleep Disordered Breathing or those who are already successfully using CPAP may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a more effective and comfortable treatment option for patients with sleep disordered breathing, potentially improving their overall health and quality of life.

How similar studies have performed: While there have been various approaches to treating SDB, the specific auto-titrating technology proposed in this research is relatively novel and has not been widely tested in this form.

Where this research is happening

ELLSWORTH, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.