A device for women to use on-demand contraception without hormones

Multipurpose Device for Female-initiated Nonsteroidal On-Demand Contraception

NIH-funded research St. Louis College of Pharmacy · NIH-11063385

This study is testing a new, hormone-free contraceptive device that women can use on their own, which works by becoming thicker when it touches semen to help prevent pregnancy, offering a safe and easy option for birth control.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionSt. Louis College of Pharmacy NIH-funded
Lab location1 site (St. Louis, UNITED STATES)
Project IDNIH-11063385 on NIH RePORTER

What this research studies

This research focuses on developing an innovative contraceptive device that women can initiate themselves, which does not rely on hormones. The device uses a unique bioresponsive polymer that increases in viscosity when it comes into contact with semen, effectively preventing pregnancy. The approach aims to provide a safer and more socially acceptable alternative to traditional contraceptive methods. By utilizing a dual-compartment vaginal device, the research seeks to empower women with a non-pharmacological option for contraception that can be deployed as needed.

Who could benefit from this research

Good fit: Ideal candidates for this research are women seeking non-hormonal contraceptive options.

Not a fit: Patients who are not interested in contraception or who require hormonal contraceptive methods may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide women with a safe, effective, and hormone-free method of contraception.

How similar studies have performed: While the approach is innovative, similar bioengineering strategies in contraceptive technology have shown promise, indicating potential for success.

Where this research is happening

St. Louis, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.