NIH-funded research Sbir 1 grant

A device for treating esophageal conditions in low-resource settings

Official title: Low-Cost, Single-Use Trans-Nasal Cryotherapy Device for Low-Resource Settings

Funded at Cryoscope Medical · NIH-10761295 · Data updated 2026-11-12

This study is testing a new, easy-to-use device that cools the inside of the nose to help treat Barrett's Esophagus, a condition that can lead to esophageal cancer, especially for people who might not have access to regular hospital care.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionCryoscope Medical
NIH-funded
Lab location1 site (Dumont, United States)
Project startSeptember 26, 2023
Project endAugust 31, 2025
Funding year2023
Award (this year)$406,500
NIH project number1R43CA285125-01
Project IDNIH-10761295 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include older adults with Barrett's Esophagus or those at high risk for esophageal cancer.

Less likely to help

Patients without Barrett's Esophagus or those who do not have access to the device due to geographic limitations may not benefit from this research.

What this research studies

This research focuses on developing a low-cost, single-use trans-nasal cryotherapy device aimed at treating conditions like Barrett's Esophagus, which can lead to esophageal cancer. The device is designed to be used in low-resource settings, making it accessible for patients who may not have access to traditional hospital-based treatments. By utilizing a non-invasive approach, the device aims to reduce the need for sedation and hospital visits, thereby improving patient comfort and convenience. The research will explore the effectiveness of this device in preventing the progression of esophageal cancer in at-risk populations.

Why it matters

Potential benefit: If successful, this research could provide a more accessible and affordable treatment option for patients at risk of esophageal cancer.

How similar studies have gone: Similar approaches using non-invasive techniques for cancer prevention have shown promise, but this specific device is a novel development.

Where this research is happening

  • Cryoscope Medical
    Dumont, United States
    Active

Researchers

  • Principal investigator: Rahimzadeh, Jason H — Cryoscope Medical
  • Study coordinator: Rahimzadeh, Jason H

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.