A device for real-time monitoring and predicting outcomes in cardiovascular surgeries and sepsis.
Official title: A real-time monitoring and predictive device for cardiovascular surgeries and sepsis
Funded at Arizona State University-Tempe Campus · NIH-11040890 · Data updated 2026-11-12
This study is working on a new device that can quickly check for sepsis during heart surgeries by analyzing urine, helping doctors catch this serious condition early and improve patient care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Arizona State University-Tempe Campus NIH-funded |
| Lab location | 1 site (Tempe, United States) |
| Project start | April 7, 2025 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $412,250 |
| NIH project number | 1R61HL173926-01A1 |
| Project ID | NIH-11040890 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include patients undergoing cardiovascular surgeries or those at risk of developing sepsis.
✕Less likely to help
Patients with non-cardiovascular conditions or those not at risk for sepsis may not benefit from this research.
What this research studies
This research focuses on developing a real-time monitoring device that can predict and diagnose sepsis, a severe condition that can arise during cardiovascular surgeries. By utilizing non-invasive urine analysis and biomarkers, the device aims to provide rapid diagnosis and intervention, potentially saving lives and preserving organ function. The approach includes algorithm development for accurate detection of sepsis, which is often challenging due to nonspecific symptoms. The research team has conducted preliminary animal studies to assess the effectiveness of urine biomarkers in diagnosing sepsis.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnosis of sepsis, significantly improving patient outcomes during critical medical situations.
How similar studies have gone: Other research has shown promise in using non-invasive methods for diagnosing sepsis, indicating that this approach could be a meaningful advancement in the field.
Where this research is happening
-
Arizona State University-Tempe Campus
Tempe, United States Active
Researchers
- Principal investigator: Forzani, Erica Silvia — Arizona State University-Tempe Campus
- Study coordinator: Forzani, Erica Silvia
Related research
Other NIH-funded projects on the same topics.
-
Role of blood flow mechanics and transfusion in sepsis-related tiny-cl vessel clots
A patient-focused look at how red blood cell flow and transfusions might influence tiny blood vessel clots and organ problems in sepsis.
-
STeroids and enhanced Antibiotics for sepsis in Africa with HIV/TB (STARS)
This grant tests whether adding steroids and stronger antibiotics helps adults with severe sepsis tied to HIV/TB in areas with high TB rates.
-
Steroids and better antibiotics for sepsis in people with AIDS in Africa
This study tests whether adding hydrocortisone and stronger antibiotics can improve survival for adults with sepsis who also have AIDS or advanced immune suppression in regions with high TB.
-
Coordinating ARDS, Pneumonia, and Sepsis research to improve care
A national coordinating center helps researchers studying ARDS and related infections work together more efficiently to learn what helps patients recover.
-
Role of MMP3 in heart dysfunction during sepsis
This research tests whether blocking MMP3 can protect the heart and improve survival during sepsis in adults.
-
Sepsis patient care guided by Ugandan-wide immune profiling
A large NIH-funded study will map how the immune system behaves during sepsis in people in Uganda to improve personalized care for sepsis patients.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.