A device for quick diagnosis of sickle cell disease
Point of care diagnostic for sickle cell disease
This study is working on a handy device that can quickly check for sickle cell disease by looking at your red blood cells, helping doctors better manage your condition and predict painful episodes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10739074 on NIH RePORTER |
What this research studies
This research aims to develop a portable device that can quickly diagnose sickle cell disease (SCD) by analyzing red blood cells (RBCs) at the point of care. Using advanced imaging technology, the device will create detailed holograms of individual RBCs to assess the presence of sickled cells, which are indicative of SCD. By employing machine learning algorithms, the device will provide quantitative data that can help predict painful vaso-occlusive crises (VOCs) and improve patient management. This innovative approach seeks to enhance routine monitoring and treatment strategies for SCD patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with sickle cell disease, particularly those experiencing frequent pain crises.
Not a fit: Patients who do not have sickle cell disease or those who are not experiencing symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective management of sickle cell disease, reducing pain crises and improving quality of life for patients.
How similar studies have performed: Other research has shown promise in using advanced imaging techniques for blood analysis, suggesting that this approach could be effective for sickle cell disease as well.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Wax, Adam — Duke University
- Study coordinator: Wax, Adam
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.