A device for providing pain relief through electrical nerve blocks.

Minimally Invasive On Demand Electrical Nerve Block (OD-ENB) Device for Peripheral Pain

NIH-funded research H-Cubed, INC. · NIH-10482175

This study is testing a new, easy-to-use device that sends gentle electrical signals to help relieve knee pain for people with osteoarthritis, aiming to improve their movement and daily life without the need for surgery or strong pain medications.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionH-Cubed, INC. NIH-funded
Lab location1 site (Olmsted Falls, United States)
Project IDNIH-10482175 on NIH RePORTER

What this research studies

This research focuses on developing a minimally invasive device that delivers on-demand electrical nerve blocks to alleviate pain associated with knee osteoarthritis (KOA). The approach aims to provide immediate pain relief without the need for invasive procedures or opioid medications, which can have significant side effects. By utilizing electrical stimulation, the device seeks to improve mobility and quality of life for patients suffering from KOA. The methodology involves testing the device's effectiveness in reducing pain and enhancing physical function in patients who have not responded well to traditional treatments.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults suffering from knee osteoarthritis who experience significant pain and have not found relief through conventional treatments.

Not a fit: Patients with conditions unrelated to knee osteoarthritis or those who are not experiencing significant pain may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could offer a new, effective pain management option for patients with knee osteoarthritis, reducing reliance on opioids and improving overall quality of life.

How similar studies have performed: Previous research has shown promise in using electrical nerve stimulation for pain management, indicating potential success for this novel approach.

Where this research is happening

Olmsted Falls, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions degenerative joint disease
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.