A device for providing pain relief through electrical nerve blocks.
Official title: Minimally Invasive On Demand Electrical Nerve Block (OD-ENB) Device for Peripheral Pain
Funded at H-Cubed, INC. · NIH-10482175 · Data updated 2026-11-12
This study is testing a new, easy-to-use device that sends gentle electrical signals to help relieve knee pain for people with osteoarthritis, aiming to improve their movement and daily life without the need for surgery or strong pain medications.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H-Cubed, INC. NIH-funded |
| Lab location | 1 site (Olmsted Falls, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2023 |
| Award (this year) | $260,384 |
| NIH project number | 1R41DA056250-01 |
| Project ID | NIH-10482175 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults suffering from knee osteoarthritis who experience significant pain and have not found relief through conventional treatments.
✕Less likely to help
Patients with conditions unrelated to knee osteoarthritis or those who are not experiencing significant pain may not benefit from this research.
What this research studies
This research focuses on developing a minimally invasive device that delivers on-demand electrical nerve blocks to alleviate pain associated with knee osteoarthritis (KOA). The approach aims to provide immediate pain relief without the need for invasive procedures or opioid medications, which can have significant side effects. By utilizing electrical stimulation, the device seeks to improve mobility and quality of life for patients suffering from KOA. The methodology involves testing the device's effectiveness in reducing pain and enhancing physical function in patients who have not responded well to traditional treatments.
Why it matters
Potential benefit: If successful, this research could offer a new, effective pain management option for patients with knee osteoarthritis, reducing reliance on opioids and improving overall quality of life.
How similar studies have gone: Previous research has shown promise in using electrical nerve stimulation for pain management, indicating potential success for this novel approach.
Where this research is happening
-
H-Cubed, INC.
Olmsted Falls, United States Active
Researchers
- Principal investigator: Vrabec, Tina Louise — H-Cubed, INC.
- Study coordinator: Vrabec, Tina Louise
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.