A device for at-home brain stimulation to help with depression

XCSITE 300: Cloud-Enabled Closed-Loop Transcranial Current Stimulation Device for At-Home Studies

NIH-funded research Pulvinar Neuro LLC · NIH-11042227

This study is testing a new device that uses gentle brain stimulation to help people manage their depression from the comfort of home, making treatment more personalized and accessible.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionPulvinar Neuro LLC NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-11042227 on NIH RePORTER

What this research studies

This research focuses on developing a cloud-enabled device that uses targeted brain stimulation to help manage depression. It employs a closed-loop system that monitors brain activity in real-time and adjusts the stimulation accordingly, aiming to provide a more personalized treatment approach. The device integrates EEG technology to measure brain signals and applies gentle electrical currents to modulate brain activity. By allowing patients to use this technology at home, the research seeks to improve accessibility and effectiveness in treating depression.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with clinical depression who are seeking alternative treatment options.

Not a fit: Patients with severe neurological disorders or those who are not able to use the device due to physical limitations may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for patients suffering from depression.

How similar studies have performed: Previous research has shown promising results with similar closed-loop brain stimulation approaches, indicating potential for success in this novel application.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.