A database for understanding how small molecules interact with proteins
BindingDB: An Open Knowledgebase of Protein-Small Molecule Interactions
This study is working on building a helpful resource that gathers information about how small molecules interact with proteins, which can assist researchers and doctors in discovering new medicines and improving treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10913388 on NIH RePORTER |
What this research studies
This research focuses on creating and expanding a comprehensive knowledgebase that catalogs the interactions between small organic molecules and proteins, known as ligands. By collecting and organizing this information, the project aims to make it more accessible for researchers and healthcare professionals. The knowledgebase will support drug design efforts, help identify new therapeutic agents, and enhance the development of computational tools for predicting how these molecules bind to proteins. This initiative will ultimately facilitate advancements in biomedical research and treatment options.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with conditions that could be treated by new drugs developed from the insights gained through the knowledgebase.
Not a fit: Patients with conditions that are not addressed by small molecule therapies may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved drug discovery and development, resulting in more effective treatments for various diseases.
How similar studies have performed: Previous research has demonstrated success in utilizing similar databases for drug discovery and development, indicating a promising approach.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Gilson, Michael K. — University of California, San Diego
- Study coordinator: Gilson, Michael K.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.