A database for understanding gene regulation in fruit flies and other insects
REDfly: The regulatory sequence resource for Drosophila and other insects
This study is building a helpful database that collects important information about how genes are controlled in fruit flies and other insects, which can help scientists understand genetic issues related to birth defects and diseases, and improve methods for controlling disease-carrying insects.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of New York at Buffalo NIH-funded |
| Lab location | 1 site (Amherst, United States) |
| Project ID | NIH-10691413 on NIH RePORTER |
What this research studies
This research focuses on creating the REDfly database, which catalogs transcriptional regulatory elements that control gene expression in Drosophila and other insects. By providing detailed information on cis-regulatory modules and transcription factor binding sites, the database aims to fill a critical gap in genomic resources. This information is essential for understanding the genetic basis of birth defects and chronic diseases, as well as for advancing biotechnological applications in disease vector control. The database will support various research areas, including genomics, machine learning, and gene regulatory network modeling.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals affected by congenital abnormalities or chronic diseases linked to genetic factors.
Not a fit: Patients with conditions unrelated to genetic regulation or those not affected by congenital abnormalities may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of genetic factors contributing to birth defects and chronic diseases, potentially leading to improved prevention and treatment strategies.
How similar studies have performed: Other research has successfully utilized similar databases to advance our understanding of gene regulation, making this approach both relevant and promising.
Where this research is happening
Amherst, United States
- State University of New York at Buffalo — Amherst, United States (Active)
Researchers
- Principal investigator: Halfon, Marc S — State University of New York at Buffalo
- Study coordinator: Halfon, Marc S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.