NIH-funded research R01 grant

A culturally tailored diet to improve heart and metabolic health in Puerto Rico

Official title: A culturally-tailored dietary trial for cardiometabolic health in Puerto Rico

Funded at Harvard School of Public Health · NIH-11061241 · Data updated 2026-11-12

This study is looking to help adults in Puerto Rico improve their heart and metabolic health by encouraging a diet that fits their culture, and it’s for people who have at least one risk factor for type 2 diabetes or heart disease.

More Cardiometabolic Health research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHarvard School of Public Health
NIH-funded
Lab location1 site (Boston, United States)
Project startJuly 19, 2023
Project endJanuary 31, 2028
Funding year2025
Award (this year)$515,693
NIH project number5R01MD018750-03
Project IDNIH-11061241 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 30-65 living in Puerto Rico who have at least one risk factor for cardiovascular disease or type 2 diabetes but do not currently have these conditions.

Less likely to help

Patients who are under 30 years old or already diagnosed with cardiovascular disease or type 2 diabetes may not benefit from this research.

What this research studies

This research aims to improve heart and metabolic health among adults in Puerto Rico by promoting a culturally appropriate diet. It builds on previous findings that a Mediterranean diet can lower the risk of type 2 diabetes and cardiovascular disease, but adapts this approach to fit the local culture and food availability. The study will involve a two-year trial with 250 participants who have at least one risk factor for these conditions, focusing on the effectiveness of this tailored dietary intervention compared to standard healthy eating programs. Participants will be monitored for changes in their health markers, such as blood pressure and cholesterol levels.

Why it matters

Potential benefit: If successful, this research could lead to significant improvements in heart and metabolic health for participants, potentially reducing the risk of diabetes and cardiovascular diseases.

How similar studies have gone: Previous studies, such as the PREDIMED trial, have shown that Mediterranean diets can significantly improve health outcomes, suggesting that culturally tailored dietary interventions may also be effective.

Where this research is happening

  • Harvard School of Public Health
    Boston, United States
    Active

Researchers

  • Principal investigator: Mattei, Josiemer — Harvard School of Public Health
  • Study coordinator: Mattei, Josiemer

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.