A core facility for induced pluripotent stem cells related to Alzheimer's disease research
Core H: iPSC Core
This study is all about creating a special collection of stem cells to help researchers learn more about Alzheimer's disease and related dementias, so they can find better ways to treat these conditions.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11114241 on NIH RePORTER |
What this research studies
This research focuses on creating and maintaining a repository of induced pluripotent stem cell (iPSC) lines specifically for Alzheimer's disease and related dementias (ADRD). The iPSC Core at Johns Hopkins University provides these stem cells to researchers both locally and nationally, facilitating studies that could lead to better understanding and treatment of ADRD. The core also offers training and expertise to investigators, ensuring that the research community can effectively utilize these valuable resources. By collaborating with other research cores, the iPSC Core aims to expand its collection of cell lines derived from well-characterized participants.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals diagnosed with Alzheimer's disease or related dementias, as well as those with specific genetic mutations associated with these conditions.
Not a fit: Patients who do not have Alzheimer's disease or related dementias may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to significant advancements in understanding and treating Alzheimer's disease and related dementias.
How similar studies have performed: Previous research utilizing induced pluripotent stem cells has shown promise in understanding neurodegenerative diseases, indicating that this approach could be beneficial.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Xu, Jinchong — Johns Hopkins University
- Study coordinator: Xu, Jinchong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.