NIH-funded research NIH-funded research

A computerized program to help veterans manage depression and get back to functioning

Official title: A Randomized Controlled Trial of Deprexis; Evaluation of A Computerized Intervention to Decrease Depression and Restore Functioning in Veterans

Funded at Olin Teague Veterans Center · NIH-11310872 · Data updated 2026-11-12

A computer-based depression program (Deprexis) is being tested to help veterans feel better and return to work and daily activities.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOlin Teague Veterans Center
NIH-funded
Lab location1 site (Temple, United States)
Project startMay 1, 2024
Project endApril 30, 2029
Funding year2026
NIH project number5IK2RX004565-03
Project IDNIH-11310872 on NIH RePORTER

Who could benefit from this research

Could help

Veterans with depressive symptoms who have access to the internet and are willing to use a computer-based therapy.

Less likely to help

Veterans with severe depression requiring immediate in-person care or those without internet access may not benefit.

What this research studies

This project tests a web- or computer-based therapy that uses cognitive-behavioral and other supportive techniques to reduce depressive symptoms in veterans who recently left or returned from deployment. It includes a randomized design to measure how well the program works compared with standard care, and it will also include interviews to learn how veterans experience the intervention. The researchers aim to understand who benefits most from the digital program and how to tailor it to veterans’ needs. The study is led by the VA/Temple collaboration at the Olin Teague Veterans Center and will involve Veterans who have depressive symptoms and access to internet-enabled devices.

Why it matters

Potential benefit: If successful, veterans could access a convenient, lower-cost option to reduce depression and improve daily functioning.

How similar studies have gone: Previous studies in general populations showed Deprexis can reduce depressive symptoms; effectiveness in Veterans is being tested here.

Where this research is happening

  • Olin Teague Veterans Center
    Temple, United States
    Active

Researchers

  • Principal investigator: Pearson, Rahel — Olin Teague Veterans Center
  • Study coordinator: Pearson, Rahel

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.