A computerized program to help veterans manage depression and get back to functioning
Official title: A Randomized Controlled Trial of Deprexis; Evaluation of A Computerized Intervention to Decrease Depression and Restore Functioning in Veterans
Funded at Olin Teague Veterans Center · NIH-11310872 · Data updated 2026-11-12
A computer-based depression program (Deprexis) is being tested to help veterans feel better and return to work and daily activities.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Olin Teague Veterans Center NIH-funded |
| Lab location | 1 site (Temple, United States) |
| Project start | May 1, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| NIH project number | 5IK2RX004565-03 |
| Project ID | NIH-11310872 on NIH RePORTER |
Who could benefit from this research
✓Could help
Veterans with depressive symptoms who have access to the internet and are willing to use a computer-based therapy.
✕Less likely to help
Veterans with severe depression requiring immediate in-person care or those without internet access may not benefit.
What this research studies
This project tests a web- or computer-based therapy that uses cognitive-behavioral and other supportive techniques to reduce depressive symptoms in veterans who recently left or returned from deployment. It includes a randomized design to measure how well the program works compared with standard care, and it will also include interviews to learn how veterans experience the intervention. The researchers aim to understand who benefits most from the digital program and how to tailor it to veterans’ needs. The study is led by the VA/Temple collaboration at the Olin Teague Veterans Center and will involve Veterans who have depressive symptoms and access to internet-enabled devices.
Why it matters
Potential benefit: If successful, veterans could access a convenient, lower-cost option to reduce depression and improve daily functioning.
How similar studies have gone: Previous studies in general populations showed Deprexis can reduce depressive symptoms; effectiveness in Veterans is being tested here.
Where this research is happening
-
Olin Teague Veterans Center
Temple, United States Active
Researchers
- Principal investigator: Pearson, Rahel — Olin Teague Veterans Center
- Study coordinator: Pearson, Rahel
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Using a computer program to help reduce depression in veterans
This study is looking at how well a computer program called Deprexis can help veterans who are feeling depressed, making it easier for them to get support and share their thoughts about mental health treatment.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.