A Compact Heart Pump for Severe Heart Failure
Development of a Minimally Invasive Single Cannulation, Compact Single Port Pulsatile Ventricular Assist Device (sppVAD) for Total LV Support
This project is creating a new, easy-to-use heart pump to help people with severe heart failure recover or prepare for a heart transplant.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | W-Z Biotech, LLC NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project ID | NIH-11193812 on NIH RePORTER |
What this research studies
Cardiogenic shock is a very serious condition where your heart can't pump enough blood, leading to organ damage and a high risk of death. Current temporary heart support devices often require major open-chest surgery or keep you confined to a hospital bed with limited movement. This new device aims to provide full heart support through a less invasive procedure, allowing patients to move around more easily. The goal is to help patients recover, bridge them to a long-term heart assist device, or prepare them for a heart transplant, potentially even allowing them to go home with the device.
Who could benefit from this research
Good fit: Patients experiencing severe cardiogenic shock who need temporary mechanical support for their left ventricle would be ideal candidates.
Not a fit: Patients with less severe heart conditions or those who do not require total left ventricular support may not benefit from this specific device.
Why it matters
Potential benefit: If successful, this device could offer a less invasive and more mobile option for temporary heart support, improving recovery and quality of life for patients with severe heart failure.
How similar studies have performed: While existing devices provide some support, this approach aims to combine minimal invasiveness with total left ventricular support and ambulation, addressing a current gap in temporary mechanical circulatory support.
Where this research is happening
Lexington, United States
- W-Z Biotech, LLC — Lexington, United States (Active)
Researchers
- Principal investigator: Topaz, Stephen R — W-Z Biotech, LLC
- Study coordinator: Topaz, Stephen R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.