A community-led program to prevent substance misuse and improve pain care for Lumbee and other American Indian people

Building iCRISP: Indigenous Community-Informed Research Infrastructure to address Substance Misuse and Pain Management

['FUNDING_OTHER'] · LUMBEE LAND DEVELOPMENT, INC. · NIH-11369461

This project will build a Lumbee-led research network to help prevent substance misuse and make pain care more culturally appropriate for Lumbee and nearby American Indian communities.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorLUMBEE LAND DEVELOPMENT, INC. (nih funded)
Locations1 site (PEMBROKE, UNITED STATES)
Trial IDNIH-11369461 on ClinicalTrials.gov

What this research studies

You would see the Lumbee Tribe lead a two-year effort to create a community-informed research network focused on substance misuse and pain management in Robeson County. Tribal leaders are partnering with a community relief organization, the state public health injury-prevention team, and several research groups to design data systems, outreach, and culturally respectful study methods. The team will hold planning workshops, collect local health information, and set priorities so future programs and studies match community needs. This planning phase does not deliver new medical treatments but aims to make future prevention and care efforts more accessible and acceptable to Lumbee and other American Indian people.

Who could benefit from this research

Good fit: Ideal participants or beneficiaries are Lumbee tribal members and other American Indian adults in Robeson County who have chronic pain, a history of substance misuse, or are at risk for substance-related harms.

Not a fit: People outside the Lumbee/Robeson County area or those without concerns about pain or substance misuse are unlikely to benefit directly from this planning initiative.

Why it matters

Potential benefit: If successful, this could lead to culturally tailored prevention and pain-treatment programs that reduce overdose and improve access to respectful care for tribal members.

How similar studies have performed: Community-based and tribal-partnership efforts have shown promise in reducing substance-related harms, but creating a dedicated, tribe-led research infrastructure for the Lumbee is a newer approach.

Where this research is happening

PEMBROKE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.