A common medication for severe obesity in children
Toward Repurposing a Commonly-Used Medication for the Treatment of Pediatric Severe Obesity
['FUNDING_R01'] · UNIVERSITY OF MINNESOTA · NIH-11115706
This project is testing if a common medication, along with lifestyle changes, can help children aged 6 to under 12 manage severe obesity.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MINNESOTA (nih funded) |
| Locations | 1 site (MINNEAPOLIS, UNITED STATES) |
| Trial ID | NIH-11115706 on ClinicalTrials.gov |
What this research studies
Severe obesity in children is a serious and long-lasting health issue that often continues into adulthood. While lifestyle changes are important, they are not always enough to significantly reduce weight. This project aims to find safe, effective, and affordable medications to help children with severe obesity. Researchers are conducting a pilot clinical trial to see if a commonly used medication, lisdexamfetamine, can be a helpful addition to lifestyle therapy for these children.
Who could benefit from this research
Good fit: Ideal candidates for this type of research would be children aged 6 to under 12 years old who have severe obesity.
Not a fit: Patients outside the specified age range or those without severe obesity may not directly benefit from this particular medication approach.
Why it matters
Potential benefit: If successful, this medication could offer a new, safe, and effective option to help children with severe obesity achieve better health outcomes.
How similar studies have performed: While psychostimulants are known to have a favorable effect on weight and a long safety record, this specific application for pediatric severe obesity is being explored in a pilot clinical trial.
Where this research is happening
MINNEAPOLIS, UNITED STATES
- UNIVERSITY OF MINNESOTA — MINNEAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FOX, CLAUDIA K — UNIVERSITY OF MINNESOTA
- Study coordinator: FOX, CLAUDIA K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.