NIH-funded research NIH-funded research

A clinical trials site in South Africa advancing HIV-related cervical cancer research

Official title: CAPRISA CASCADE Clinical Trials Network Clinical Research Site

Funded at Centre/aids Programme/res/south Africa · NIH-11413352 · Data updated 2026-11-12

A dedicated clinical trial site in KwaZulu-Natal, South Africa, is building infrastructure to run pragmatic trials addressing HIV and AIDS-related cervical cancer.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionCentre/aids Programme/res/south Africa
NIH-funded
Lab location1 site (Durban, SOUTH AFRICA)
Project startSeptember 5, 2023
Project endMay 31, 2028
Funding year2026
Award (this year)$91,242
NIH project number5UG1CA284671-04
Project IDNIH-11413352 on NIH RePORTER

Who could benefit from this research

Could help

Women living with HIV in KwaZulu-Natal, South Africa, and other eligible participants in CAPRISA CASCADE trials.

Less likely to help

Individuals not eligible for trial participation or not residing in the trial network may not benefit from this site-level infrastructure.

What this research studies

This grant supports CAPRISA CASCADE to provide trial sites, leadership, and operations for pragmatic clinical studies at an established research center in Durban. The site leverages its experience with HIV prevention and management to study cervical cancer in the context of HIV in a region heavily affected by both conditions. The team will recruit eligible participants, coordinate with a network of trial sites, and manage data collection to ensure rigorous, real-world results. The focus is on improving prevention, screening, and treatment pathways for women living with HIV who are at risk for or affected by cervical cancer.

Why it matters

Potential benefit: If successful, the work could improve access to effective HIV-related cervical cancer prevention and care for women in high-burden settings.

How similar studies have gone: CAPRISA has a long track record in HIV-related research and has conducted high-quality clinical trials, suggesting potential for successful pragmas.

Where this research is happening

  • Centre/aids Programme/res/south Africa
    Durban, South Africa
    Active

Researchers

  • Principal investigator: Naicker, Nivashnee — Centre/aids Programme/res/south Africa
  • Study coordinator: Naicker, Nivashnee

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.