A centralized resource to measure HIV latent and expressed reservoirs
Official title: Centralized Resource to Accurately Quantify Latent and Expressed HIVReservoirs
Funded at Accelevir Diagnostics, LLC · NIH-11609197 · Data updated 2026-11-12
A patient-facing resource will help researchers accurately measure hidden HIV reservoirs and how they respond to treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Accelevir Diagnostics, LLC NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | April 13, 2020 |
| Project end | March 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $531,874 |
| NIH project number | 3R24AI143502-07S1 |
| Project ID | NIH-11609197 on NIH RePORTER |
Who could benefit from this research
✓Could help
People living with HIV who are on antiretroviral therapy and potentially eligible for future reservoir-targeting trials.
✕Less likely to help
Patients not involved in reservoir-targeting trials or not on antiretroviral therapy may not directly benefit.
What this research studies
This project builds a centralized system to quantify latent and expressed HIV reservoirs, with the goal of improving how we track the virus in people living with HIV. It focuses on measuring the tiny population of resting memory CD4+ T cells that harbor HIV and can rekindle infection if therapy stops. Researchers will use validated assays and standardized methods to quantify these reservoirs across tissues. By improving measurement, future therapies can be guided toward eradicating the virus and achieving a cure. The effort is designed to translate complex laboratory techniques into practical tools that may inform patient care and trial participation.
Why it matters
Potential benefit: If successful, it could accelerate the development of curative strategies by providing reliable reservoir measurements that guide treatment decisions and trial designs.
How similar studies have gone: Previous efforts have advanced reservoir measurement, but this project aims to standardize and centralize the approach for broader utility.
Where this research is happening
-
Accelevir Diagnostics, LLC
Baltimore, United States Active
Researchers
- Principal investigator: Laird, Gregory Michael — Accelevir Diagnostics, LLC
- Study coordinator: Laird, Gregory Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.